Study the Effects of Some Herbs on Rats Suffering from Diabetes

This investigation aimed to evaluate the effect of colocynth, teucrium and their combination on male diabetic rats. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (fed on basal diet). Group (3): Diabetic rats fed on basal diet containing 5% colocynth .Group (4): Diabetic rats fed on basal diet containing 5% teucrium. Group (5): Diabetic rats fed on basal diet containing mixture of them (5%). At the end of experiment, 28 days of feeding, all serum samples were analyzed for biochemical parameters. Injection with alloxan caused a significant decrease in BWG and high density lipoprotein cholesterol (HDL-c) while a significant increase was recorded in Total cholesterol (TC), triglyceride (TG), very low density lipoprotein cholesterol (VLDL-c), low density lipoprotein cholesterol (LDL-c), uric acid (U.A), Creatinine, Urea, Aspartate amino transaminase (AST), alanine amino transferase (ALT), Alkaline phosphatase (ALP) and Glucose. Diabetic rats treated with various diets, showed the improvement in all previous parameters.