Possible Effects of Sweet Potato Leaves, Roots and their Mixture Feeding on Alloxan-Induced Diabetic Ratsm

Refaat, Wafaa; El-Kholie, Emad; El-Nasr, Abeer

doi:10.21608/mkas.2020.157730

Possible Effects of Sweet Potato Leaves, Roots and their Mixture Feeding on Alloxan-Induced Diabetic Ratsm

Document Type : Original research articles

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10.21608/mkas.2020.157730

Abstract

The present study was designed to study the effect of sweet potato (Ipomoea batatas, L.) leaves, roots and their mixture on diabetic rats. Forty eight adult male albino rats were used in this study, weighting (150±10g) were divided into eight groups, six rats each. Sweet potatoleaves, roots and their mixture as powder were added at percent 2.5 % and 5% from the main diet for 28 days. Diabetic rats were induced alloxan subcutaneously injection (150 mg/kg body weight). Serum lipid profiles (TG, TC, LDL-c, VLDL-c, HDL-c), serum glucose, liver enzymes activities (ALT, AST and ALP) and kidney functions (creatinine, uric acid and urea levels) were also determined. From the obtained results it could be concluded that feeding on sweet potatoleaves, roots and their mixture as powder caused significant (P ≤ 0.05) increase in HDL-c, as compared with control (-ve) group, and enhanced the kidney and liver functions with the decrease of ALT, AST, ALP, serum glucose, creatinine, uric acid and urea which reflects the powerful nutraceutical therapeutic effects. Feeding on sweet potatoleaves, roots and their mixture, as a powder attenuated diabetic effects in rats, the best result was to concentrate 5% mixture of sweet potato leaves and roots powder.

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