The Effect of Arachidonic acid and calcium deposition on Bony mass in experimental animal

Document Type : Original research articles

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Abstract

Bones  are one of the most  important parts of the human body ,as weak bones  may lest  to general weakness as  it shields for  all body system .
Arachidonic acid is a polyunsaturated fatty acid present in the phospholipids(especially phosphatidylethanolamine, phosphatidylcholine, and phosphatidylinositides) of membranes of the body's cells, and is abundant in the brain, muscles, and liver. Skeletal muscle is an especially active site of arachidonic acid retention, accounting for roughly 10-20% of the phospholipid fatty acid content on average. It still plays  fundament al role  in reducing pathogenicity.
            This study aim to Investigated the effect of Arachidonic acid(deficiency & treatment) on calcium deposition and bones density. Compare the results of those groups with the group affected by decrease Arachidonic acid and increase calcium deposition .
Experimental design:
            Thirty sex healthy adult male albino rats were fed on standard diet for one week for adaptation. After this week, they were divided into six groups, The first group (6 rats) fed on basal diet (as a negative control group).
            The second group (6 rats) fed on standard diet without aracidonic acid  and double dose of calcium
(as a positive control group).
The third group (6rats) fed on standard diet with aracidonic acid( 1000 mg) and the double dose of calcium
The fourth group (6 rats) fed on standard diet with aracidonic ac id(1150mg ) and the double dose of calcium
            The five group (6 rats) fed on standard diet with aracidonic acid (1300 mg) and the double dose of calcium
The last group (6 rats) fed on standard diet with aracidonic acid (1450 mg) and the double dose of calcium
 Conclusion:
Results obtained for this study led to several conclusions:
it is important for The Relation ship between Arachidonic acid and first time  walking in children bone mass increase and the best Results  in 1450 mg.

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